A randomised controlled clinical trial to assess efficacy of convergent ablation with the LARIAT procedure, as compared to standard endocardial catheter ablation in patients with long-standing persistent atrial fibrillation (AF).
Age > 18 years; < 80 years
Persistent AF > 1-year duration
Left atrium size < 6cm
Pts should be able to provide written informed consent.
Subjects currently enrolled in another investigational study except in case of observational registry with no associated treatments.
Subject has a reversible cause of AF or transient AF
Subject is absent of LAA or if the LAA is previously surgically ligated
Subject has had previous cardiac surgery or abdominal surgery.
Barts & The London NHS Trust
Lead sponsor
AtriCure, Inc.
Collaborator