COOLEY- Study: aCute On chrOnic Liver failurE Using the cYtosorb Device
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity Hospital, Antwerp
About this trial
A Prospective, Single-Center trial, in Patients With Acute on Chronic Liver Failure. Study of Standard Medical Care Plus CytoSorb® Compared to Standard Medical Care Alone in a historical group.
Eligibility criteria
Qualifiers
adult patients (≥ 18 years) admitted to the University Hospital of Antwerp (UZA), Belgium.
Written informed consent from patient or if not possible due to encephalopathy (> grade 2): legal representative
Acute decompensation event (identifiable trigger)
Hepatic encephalopathy grade ≥ 2
Disqualifiers
• known patient will against participation in the study or against the measures applied in the study
a decision made prior to inclusion to stop further treatment of the patient within the next 24 hours
no complete remission of malignancy including hepatocellular carcinoma within the past 12 months
ongoing intermittent or CRRT before study inclusion
Trial design
Treatments tested in this trial
- CytoSorb
Treatment groups
20 Participants
are divided into 2 treatment groupsSponsors and collaborators
University Hospital, Antwerp
Lead sponsor
CytoSorbents Europe GmbH
Collaborator
Source ClinicalTrials.gov