This study aims to investigate the guiding value of coronary CTA combined with CT-FFR in diagnostic and treatment decision-making for emergency chest pain patients at moderate risk, as well as its impact on clinical outcomes. Through a prospective multicenter randomized controlled trial, this research compares the preventive effects of early application of this technology versus standard care on major adverse cardiovascular and cerebrovascular events (MACCE), with the goal of optimizing the diagnostic and treatment processes for emergency chest pain patients.
Age≥18 years；
Within 24 hours of presenting to the emergency department (ED) with chest pain or other symptoms suggestive of coronary artery disease (CAD)；
HEART-score >3 (according to http://www.heartscore.nl/)；
Signed written informed consent.
Inability to obtain informed consent；
Acute Coronary Syndromes (ACS) requiring urgent revascularization；
Known Obstructive Coronary Artery Disease (CAD) or previous PCI or CABG;
Concomitant severe congestive heart failure (New York Heart Association [NYHA] class III-IV or left ventricular ejection fraction [LVEF] < 30%) or acute pulmonary edema;
Qilu Hospital of Shandong University
Lead sponsor
The Affiliated Hospital of Qingdao University
Collaborator
Second Affiliated Hospital, School of Medicine, Zhejiang University
Collaborator
Beijing Anzhen Hospital
Collaborator
JiNing NO.1 People Hospital
Collaborator
Zhun Ge Er Qi Central Hospital
Collaborator