Coronary Computed Tomography AngioGraphy Prior to Catheter Ablation in Patients With Atrial FIBrillation

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorTor Biering-Sørensen

About this trial

The purpose of this randomized, controlled trial is to investigate whether coronary computed tomography (CT) angiography prior to catheter ablation and derived treatment (medical anti-ischemic and multimodality treatment and/or mechanical revascularization) can improve clinical outcomes in patients with atrial fibrillation undergoing catheter ablation.

A sub-study will investigate the effect of different ablation strategies on clinical outcomes in patients with atrial fibrillation undergoing catheter ablation.

Eligibility criteria

Qualifiers

Age over 18 years.

Referral for catheter ablation treatment (excluding AV-junction ablation) for atrial fibrillation (both paroxysmal and persistent atrial fibrillation) at the Department of Cardiology at Gentofte Hospital. Both first ablation and re-ablation treatments are included.

The ability and willingness to provide written informed consent.

Disqualifiers

Known atherosclerotic cardiovascular disease (ASCVD).

Ongoing treatment with statins.

Contraindications for coronary CT angiography, e.g. contrast allergy

Recent coronary CT angiography including CAC-score without positive findings <3 years prior to screening.

Trial design

Treatments tested in this trial

  • Analysis of coronary CT Angiography and CAC scoring at the time of catheter ablation

Treatment groups

852 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Tor Biering-Sørensen

Lead sponsor

Herlev and Gentofte Hospital

Sponsor institution