Coronary CT-Derived FFR-Guided Strategy Versus Medical Therapy
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University
About this trial
The overall purpose of ACCURATE II trial is to compare the clinical outcomes of CT-derived FFR guided strategy versus medical therapy in patients with chronic coronary syndrome.
Eligibility criteria
Qualifiers
Age ≥ 18 years, with at least one vessel has CT-derived FFR≤0.80
Patients with chronic coronary syndromes
Signed written informed consent
Disqualifiers
The patient has a known hypersensitivity or contraindication to any of the following medications: Heparin, Aspirin, Clopidogrel, Prasugrel, Ticagrelor, Contrast media (Patients with documented sensitivity to contrast media which can be effectively pre-medicated with steroids and diphenhydramine [e.g. rash] may be enrolled)
Prior percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG)
Sinus arrhythmia, cardiogenic shock, or severe heart failure (NYHA≥III)
Inability or unwillingness to undergo CT scan or coronary angiography
Trial design
Treatments tested in this trial
- ITS plus OMT
- OMT
Treatment groups
1,066 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov