About this trial
The goal of this clinical study is to learn if a new, non-invasive monitoring method called EIT Pulse Wave can accurately measure blood flow to the lungs (pulmonary perfusion) and predict heart stroke volume (SV) in critically ill patients. It will also learn about the safety of this monitoring approach. The main questions it aims to answer are:
How well does the EIT Pulse Wave measurement of lung blood flow correlate with the SV measured by the standard method (Swan-Ganz catheter)? Can we build a reliable model to predict SV non-invasively using the EIT Pulse Wave signal? Researchers will compare the EIT Pulse Wave measurements directly with the Swan-Ganz catheter measurements to see if the new method is accurate.
Participants will:
Be critically ill adults in the ICU who are already receiving mechanical ventilation and have a Swan-Ganz catheter in place for medical reasons.
Undergo simultaneous monitoring using both the EIT device and the Swan-Ganz catheter every 30 minutes for up to 48 hours.
Have their ventilator settings adjusted to different levels as part of the study protocol while both measurements are recorded.
Eligibility criteria
Qualifiers
Critically ill patients requiring mechanical ventilation support.
Patients meeting the 2023 global ARDS definition and/or shock patients receiving vasoactive medication therapy.
Patients who have already had a pulmonary artery catheter inserted due to clinical needs.
Disqualifiers
Age under 18 years or over 80 years.
Patients with severe obesity (BMI ≥ 35 kg/m²).
Pregnant or lactating women.
Pulmonary embolism.
Trial design
Treatments tested in this trial
- Synchronous Data Acquisition of EIT and Pulmonary Artery Catheter