Cortical Excitability in Cyclic Vomiting Syndrome

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorUniversity of Pittsburgh

About this trial

This exploratory study will determine if there are differences in cortical excitability between patients suffering from cyclic vomiting syndrome (CVS) and healthy control subjects, as assessed by a non-invasive method of brain stimulation (Transcranial Magnetic Stimulation, TMS).

Eligibility criteria

Qualifiers

diagnosis of CVS

Disqualifiers

history of CVS (for healthy control population only)

psychosis or altered cognitive status

history of head injury, metal in the skull, stroke, or a history of seizures or a history of syncope (fainting or passing out)

implantable devices, such as a pacemaker or nerve stimulator

Trial design

Treatments tested in this trial

  • TMS Paired-Pulse assessment of cortical excitability
  • Autonomic activity

Treatment groups

110 Participants
are divided into 2 treatment groups

Sponsors and collaborators