Corticosteroid Injection Effectiveness in Carpel Tunnel Patients With Negative or Mild EMG Studies

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorHenry Ford Health System

About this trial

Carpal Tunnel Syndrome (CTS) is the most common nerve entrapment syndrome worldwide. There are currently no studies examining the effectiveness of corticosteroid injections in patients with normal (negative) EMG studies. The purpose of this study is to gain a better understanding of the duration of symptom improvement post corticosteroid injection in patients with negative or mild EMG studies. The Boston Carpal Tunnel Questionnaire will be given to patients undergoing corticosteroid injections for the treatment of carpal tunnel syndrome to assess their response to the injection. Investigators will collect data retrospectively. The Boston Carpal Tunnel Questionnaire (BCTQ) is administered as per standard protocol to all patients with CTS who have a negative or mild EMG study. The BCTQ assesses the patient's self-reported symptom severity and functional status. Investigators will analyze this data with respect to demographics as well as numbness in the median n. distribution, nocturnal numbness, weakness/atrophy of the thenar musculature, Tinel's sign, Phalen's test, loss of 2-point discrimination, Quick-Dash score, and grip strength score.

The primary outcome will be the Boston Carpal Tunnel Questionnaire outcome score under the different EMG conditions.The secondary outcomes will be numbness in the median n. distribution, nocturnal numbness, weakness/atrophy of the thenar musculature, Tinel's sign, Phalen's test, loss of 2-point discrimination, QuickDash score, and grip strength score. Both outcomes will be examined in patients with negative or mild EMG readings. This information will allow orthopedic physicians to gain a better understanding of the duration of symptom improvement post-corticosteroid injection, allowing them to fine tune their treatment plans for CTS patients.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients who speak English

Patients who are 18 years or older

Patients who are clinically diagnosed with CTS

Patients who have a negative or mild EMG study

Disqualifiers

Patients who do not speak English

Patients who are younger than 18 years of age

Patients who have experienced previous trauma to the wrist

Patients who have had previous treatment for CTS including but not limited to corticosteroid injection or surgery

Trial population

Patients clinically diagnosed with CTS, have a negative or mild EMG study, and receive a corticosteroid injection at Henry Ford Health System Orthopedics.

Trial design

Design model

Cohort

Time perspective

Other

Treatments tested in this trial

  • Corticosteroid injections for CTS treatment

    Other intervention

    Treatment of carpel tunnel syndrome with corticosteroid injections for EMG mild and EMG negative patients

Treatment groups

300 Participants
are divided into 2 treatment groups
Group A: Patient with CTS/Mild EMG1 intervention
Group B: Patient with CTS/Negative EMG1 intervention

Trial outcomes

Primary outcomes

1

Boston Carpel Tunnel Questionnaire

Scaled 1-5, higher scores indicate worse outcomes

Time frame
Dec 23 2020-Dec 22 2021

Secondary outcomes

1

Number of patients with numbness in the median n. distribution

Positive test includes numbness in parts of palm, thumb, second and third finger, assessed by physician

Time frame
Dec 23 2020-Dec 22 2021
2

Number of patients with weakness/atrophy of the thenar musculature

Positive test includes weakness in grip or holding objects as described by participant, assessed by physician

Time frame
Dec 23 2020-Dec 22 2021
3

Number of patients with positive Tinel's Sign

Positive sign includes 'pins and needles' in parts of palm, thumb, second and third finger upon percussion of median nerve, assessed by physician

Time frame
Dec 23 2020-Dec 22 2021
4

Number of patients with positive Phalen's Test

Positive test includes pain in parts of palm, thumb, second and third finger associated with compression of the median nerve, assessed by physician

Time frame
Dec 23 2020-Dec 22 2021

Other outcomes

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