Corticostriatal Contributions to Parkinson's Disease Cognitive Impairment

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40+
SponsorVanderbilt University Medical Center

About this trial

The goal of this study is to learn more about the brain activity underlying Parkinson's disease cognitive impairment. The investigators will utilize neural recordings from corticostriatal structures performed during deep brain stimulation surgery to measure neural activity underlying nonmotor symptoms of Parkinson's disease.

Eligibility criteria

Qualifiers

Scheduled to undergo deep brain stimulation surgery under local anesthesia at Vanderbilt University Medical Center

Planned clinical electrode trajectory that contacts caudate

Age greater than or equal to 40

Diagnosis of Parkinson's disease

Disqualifiers

Age less than 40

Not able to participate in intraoperative testing (for example unable to comprehend instructions or follow directions)

Movement disorder other than Parkinson's disease

Trial design

Treatments tested in this trial

  • Neurophysiology recordings
  • Neural stimulation

Treatment groups

75 Participants
are divided into 1 treatment group