COsegregation of VARiants in Panel of Genes
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorInstitut Curie
About this trial
The aim of the COVAR project is to achieve reliable classification of as many variants of interest as possible from the French OncoGenetics Database (FrOG, https://frog-db.fr/) in order to use them for the genetic counseling. The results obtained through this study will have a major impact on clinical management of the patients and their families conducting in some cases to propose a prophylactic surgery.
Eligibility criteria
Qualifiers
A person carrying a variant of interest in a gene analyzed in a diagnostic setting by one of the laboratories within the Genetics and Cancer Group (GGC)-Unicancer network, classified as class 3, 4 or hypomorphic class 5, and selected by the national expert group for the gene concerned.
Age ≥ 18 years.
Signed written inform consent "index case"
Any relative of an index case with cancer
Disqualifiers
Minors
Persons deprived of liberty or under guardianship (including curators).
Absence of signed written inform consent
Trial design
Treatments tested in this trial
- salivary kit
Treatment groups
11,000 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov