About this trial
The main objective of this study is to demonstrate whether the combination of chronic remote ischemic conditioning and mindfulness therapy can reduce cardiovascular adverse events in patients with incomplete revascularization of coronary artery disease.
Eligibility criteria
Qualifiers
1) Age ≥18 years old
2) Consistent with the diagnosis of coronary heart disease, complete revascularization was not performed (coronary angiography showed that at least one vessel with a reference diameter of 3.0mm had stenosis greater than 90%, and quantitative flow ratio (QFR) < 0.80)
3) Symptoms of myocardial ischemia (resting or exertional angina; Angina allele: chest tightness, shortness of breath, etc.);
Disqualifiers
Age < 18 years old
Heart failure patients with NYHA class IV, or left ventricular ejection fraction (LVEF) < 30%
Creatinine clearance <15 mL/min (or eGFR < 15 mL/min/1.73m²), or requires dialysis
Myocardial diseases such as hypertrophic cardiomyopathy, dilated cardiomyopathy, etc.
Trial design
Treatments tested in this trial
- chronic remote ischemic conditioning
- Mindfulness Therapy
- sham CRIC
- sham MFT