CRIC Combined With MFT for Cardiovascular Adverse Events in Patients With Incomplete Revascularization of CAD

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorHenan Institute of Cardiovascular Epidemiology

About this trial

The main objective of this study is to demonstrate whether the combination of chronic remote ischemic conditioning and mindfulness therapy can reduce cardiovascular adverse events in patients with incomplete revascularization of coronary artery disease.

Eligibility criteria

Qualifiers

1) Age ≥18 years old

2) Consistent with the diagnosis of coronary heart disease, complete revascularization was not performed (coronary angiography showed that at least one vessel with a reference diameter of 3.0mm had stenosis greater than 90%, and quantitative flow ratio (QFR) < 0.80)

3) Symptoms of myocardial ischemia (resting or exertional angina; Angina allele: chest tightness, shortness of breath, etc.);

Disqualifiers

Age < 18 years old

Heart failure patients with NYHA class IV, or left ventricular ejection fraction (LVEF) < 30%

Creatinine clearance <15 mL/min (or eGFR < 15 mL/min/1.73m²), or requires dialysis

Myocardial diseases such as hypertrophic cardiomyopathy, dilated cardiomyopathy, etc.

Trial design

Treatments tested in this trial

  • chronic remote ischemic conditioning
  • Mindfulness Therapy
  • sham CRIC
  • sham MFT

Treatment groups

2,000 Participants
are divided into 4 treatment groups