CRIC Combined With MFT for MFR in Patients With Incomplete Revascularization of CAD

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorHenan Institute of Cardiovascular Epidemiology

About this trial

The main objective of this study is to demonstrate whether the combination of chronic remote ischemic conditioning and mindfulness therapy can improve myocardial flow reserve in patients with incomplete revascularization of coronary artery disease.

Eligibility criteria

Qualifiers

Age ≥18 years old

Consistent with the diagnosis of coronary heart disease, complete revascularization was not performed (coronary angiography showed that at least one vessel with a reference diameter of 3.0mm had stenosis greater than 90%, and quantitative flow ratio (QFR) < 0.80)

Symptoms of myocardial ischemia (resting or exertional angina; Angina allele: chest tightness, shortness of breath, etc.);

Disqualifiers

• Age < 18 years old

Heart failure patients with NYHA class IV, or left ventricular ejection fraction (LVEF) < 30%

Creatinine clearance <15 mL/min (or eGFR < 15 mL/min/1.73m²), or requires dialysis

Myocardial diseases such as hypertrophic cardiomyopathy, dilated cardiomyopathy, etc.

Trial design

Treatments tested in this trial

  • CRIC
  • MFT
  • sham CIRC
  • sham MFT

Treatment groups

480 Participants
are divided into 4 treatment groups

Locations

This trial has no locations