Cryoablation as a Minimally Invasive Alternative to Surgery for Managing Ductal Carcinoma In Situ

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18+
SponsorGlendale Adventist Medical Center d/b/a Adventist Health Glendale

About this trial

Cryoablation or tumor freezing is a percutaneous, office-based procedure that is emerging as a minimally invasive, cost-effective alternative to surgery that is currently being evaluated in clinical trials for the management of for early-stage invasive breast cancer. The investigator will also evaluate the potential of cryoablation as a minimally invasive alternative to surgery for small areas of DCIS by examining its ability to achieve complete ablation of DCIS within the targeted cryoablation zone of necrosis.

Eligibility criteria

Qualifiers

DCIS spanning 2 cm or less based on its radiographic appearance by mammography and/or breast contrast-enhanced MRI

Diagnosis of DCIS by minimally invasive needle biopsy

No prior history of DCIS or invasive breast cancer in the same breast

No history of surgical biopsy and/or lumpectomy for diagnosis/treatment in the same breast

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Cryoablation

Treatment groups

30 Participants
are divided into 1 treatment group

Sponsors and collaborators

Glendale Adventist Medical Center d/b/a Adventist Health Glendale

Lead sponsor

Helen Rey Breast Cancer Research Foundation

Collaborator

California Oncology Research Institute

Collaborator

Doterra Healing Hands Foundation

Collaborator