About this trial
Cryoablation or tumor freezing is a percutaneous, office-based procedure that is emerging as a minimally invasive, cost-effective alternative to surgery that is currently being evaluated in clinical trials for the management of for early-stage invasive breast cancer. The investigator will also evaluate the potential of cryoablation as a minimally invasive alternative to surgery for small areas of DCIS by examining its ability to achieve complete ablation of DCIS within the targeted cryoablation zone of necrosis.
Eligibility criteria
Qualifiers
DCIS spanning 2 cm or less based on its radiographic appearance by mammography and/or breast contrast-enhanced MRI
Diagnosis of DCIS by minimally invasive needle biopsy
No prior history of DCIS or invasive breast cancer in the same breast
No history of surgical biopsy and/or lumpectomy for diagnosis/treatment in the same breast
Disqualifiers
None
Trial design
Treatments tested in this trial
- Cryoablation
Treatment groups
Sponsors and collaborators
Glendale Adventist Medical Center d/b/a Adventist Health Glendale
Lead sponsor
Helen Rey Breast Cancer Research Foundation
Collaborator
California Oncology Research Institute
Collaborator
Doterra Healing Hands Foundation
Collaborator