Current Practice of Ventilation Strategies in Children Undergoing General Anesthesia

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeUp to 16
SponsorAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

About this trial

Postoperative pulmonary complications (PPCs) are common in children undergoing general anesthesia and are associated with prolonged stay in the hospital and high costs. Development of PPCs is associated with ventilator settings in adult patients undergoing general anesthesia. Data on perioperative ventilator settings in children are lacking, leaving the anaesthetist without guidance. Consequently, the current standard of care in perioperative mechanical ventilation in children is expected to be extremely heterogeneous, leading to ventilation with higher levels of energy than necessary. Therefore, it is highly necessary to evaluate the current practice in perioperative ventilation in children and to determine associations with PPCs.

Eligibility criteria

Qualifiers

aged ≤ 16 years;

undergoing general anesthesia

airway management with tube or LMA; and

connected to mechanical ventilator . minimum duration of procedure: 15 minutes

Disqualifiers

patients undergoing surgical procedures involving extra-corporal circulation;

patients receiving ventilation with high frequency jet ventilation or high frequency oscillatory ventilation;

sedation without airway management in the form of a endotracheal tube or a supraglottic airway device; and

(rigid) bronchoscopic procedures with maintenance of spontaneous ventilation.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

10,000 Participants
are grouped into 5 trial groups