Cushing's Syndrome Before and After Treatment (CORRECT)
ConditionCushing Syndrome
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Aarhus
About this trial
The purpose of this study is to prospectively study patients with Cushing's syndrome before and after treatment, with a special emphasis on physical function, quality of life, and circadian rhythms.
The hypotheses are:
* Cushing's syndrome negatively impacts health-related quality of life (HRQoL) and physical functioning * Cushing's syndrome is associated with altered circadian rhythms at the whole body level and in peripheral target tissues. * These complications partially reverse following disease control.
Eligibility criteria
Qualifiers
ACTH-dependent CS
ACTH-independent CS
Age >18 years
Written informed consent
Disqualifiers
Active cancer
Iatrogenic or malignant cause of CS such as adrenocortical carcinoma
Chronic heart failure (New York Heart Association class IV)
Chronic kidney disease Chronic Kidney Disease stage ≥3 (eGFR >30 ml/min)
Trial design
Treatments tested in this trial
- no intervention, as this is an observational study
Treatment groups
No treatment groups listed
Sponsors and collaborators
University of Aarhus
Lead sponsor
Aarhus University Hospital
Collaborator
Source ClinicalTrials.gov