Daily Amino Acid Supplementation for People With Parkinson's Disease

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50-80
SponsorCristina Colon-Semenza

About this trial

The goal of this clinical trial is to learn if a tailored amino acid supplement works to help adults living with Parkinson's disease to improve nutrition, metabolic function, body composition, and physical and mental function. The main questions it aims to answer are:

Does the tailored amino acid supplement increase essential amino acids (nutritional status)?

Does the tailored amino acid supplement increase an antioxidant (complex amino acid) and decrease an amino acid associated with oxidative stress?

Does the tailored amino acid supplement improve physical and mental health compared to a placebo supplement?

Researchers will compare the tailored amino acid supplement to a placebo (a look-alike substance that contains no active ingredients) to see if the tailored amino acid supplements work to support health for people with Parkinson's disease.

Participants will:

Take the tailored amino acid supplement or a placebo every day for 6 months, visit the lab at baseline, after 3 months, and after 6 months for fasting blood draws, body composition assessment, and physical and mental health testing and keep a diary of their food intake and supplement intake.

Eligibility criteria

Qualifiers

Male and Females.

50-80 Years.

Previous diagnosis of idiopathic Parkinson's Disease by patient report.

Use of dopamine replacement medication (e.g. levodopa) for at least 2 years.

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Targeted Amino Acid Supplement
  • Control (placebo)

Treatment groups

30 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Cristina Colon-Semenza

Lead sponsor

University of Connecticut

Sponsor institution

United States Department of Agriculture (USDA)

Collaborator