Daily Versus Alternate-Day Oral Iron Therapy for Anemia in Second-Trimester Pregnancy
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-40
SponsorPakistan Air Force (PAF) Hospital Islamabad
About this trial
This randomized controlled trial compares daily versus alternate-day oral iron supplementation in pregnant women with iron deficiency anemia during the second trimester. The study evaluates changes in hemoglobin and serum ferritin, treatment adherence, and gastrointestinal side effects to inform more patient-centered, physiologically aligned dosing strategies.
Eligibility criteria
Qualifiers
Aged 18 to 40 years
Pregnant women in the second trimester (13 to 27 weeks gestation)
Hemoglobin below 11 g/dL with serum ferritin below 30 ng/mL
Singleton pregnancy
Disqualifiers
Known congenital or acquired hemoglobin disorders (e.g., thalassemia, hemoglobinopathies)
Chronic diseases affecting hemoglobin levels (e.g., chronic kidney disease, inflammatory disorders)
Bleeding disorders or a history of frequent blood loss
Gastrointestinal conditions impairing nutrient absorption (e.g., celiac disease or other malabsorption syndromes)
Trial design
Treatments tested in this trial
- Ferrous Sulfate
Treatment groups
184 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov