Data Clustering Study With Artificial Intelligence and Phenotyping of Patients With Acute Pulmonary Embolism

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorCentre Hospitalier Intercommunal de Toulon La Seyne sur Mer

About this trial

The aim will be to identify clinically relevant phenotypes in patients with acute pulmonary embolism. Hierarchical clustering methods combined with unsupervised learning (machine learning) will be used to obtain groups of patients who are homogeneous at diagnosis. Evaluating their prognosis at 6 months (recurrence or chronic thromboembolic pulmonary hypertension), account the first 3 months of anticoagulant treatment, would provide an aid to medical decision-making.

This research will include a retrospective and a prospective parts. The retrospective part will include patients who have been admitted to CHITS for acute pulmonary embolism since 2019. For the prospective part, it is planned to include patients with same characteristics over the years 2024 and 2025. More than 2,500 patients are expected to be included.

This research will have no impact on current patient care. Data from consultations and various examinations carried out as part of care will be collected for six months post-diagnosis in order to meet the research objectives.

Eligibility criteria

Qualifiers

Age ≥ 18 years;

Patient with acute pulmonary embolism in CHITS (hospitalised or not).

Disqualifiers

Sub-segmental pulmonary embolisms ;

Patient opposition.

Trial design

Treatments tested in this trial

  • Hierarchical clustering methods

Treatment groups

2,500 Participants
are divided into 1 treatment group