Decreasing Preoperative Stress to Prevent Postoperative Delirium and Postoperative Cognitive Decline in Cardiac Surgical Patients.

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorHeart and Brain Research Group, Germany

About this trial

Patients undergoing cardiac surgery often complain of anxiety before a major operation and the resulting stress. This circumstance is a risk factor for mental problems that may occur after the operation (e.g., delirium or memory deficits). This study aims to prevent these discomforts by a preoperative relaxation intervention.

Eligibility criteria

Qualifiers

Elective cardiac surgery (coronary artery bypass surgery, aortic or mitral valve replacement/reconstruction, or combination surgery) with standardized extracorporeal circulation.

A sufficiently good knowledge of German is necessary as neuropsychological tests are language-dependent.

Disqualifiers

History of acute clinically relevant cognitive impairment of any cause (e.g., dementia, depression, stroke, multiple sclerosis) that may impair neuropsychological evaluation.

Contraindications to the presentation of binaural beats or visual stimuli (e.g., epilepsy),

Significant hearing loss or astigmatism, which may interfere with optimal perception of auditory and visual stimuli.

Taking sedatives on the day of surgery.

Trial design

Treatments tested in this trial

  • Intervention with natural sounds administered via headphones
  • Intervention with natural sounds and binaural beats administered via headphones
  • Intervention with natural sounds and virtual reality administered via headphones and head mounted display
  • Intervention with natural sounds, binaural beats and virtual reality administered via headphones and head mounted display

Treatment groups

125 Participants
are divided into 5 treatment groups