Deep Brain Stimulation in Laryngeal Dystonia and Voice Tremor
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorMassachusetts Eye and Ear Infirmary
About this trial
The goals of this project are 1) to determine the incidence of neurological voice disorders in patients with dystonia and essential tremor undergoing deep brain stimulation (DBS), 2) investigate the neuroimaging and intracranial neurophysiology correlates of voice dysfunction in these subjects, and subsequently 3) determine the effects of DBS on voice function.
Eligibility criteria
Qualifiers
Clinical indications to proceed with DBS implantation, as determined by the clinical multidisciplinary movement disorders board, including: a) definitive diagnosis of essential tremor or dystonia, b) medically refractory disease, c) adequate performance on neuropsychological evaluation as determined by a licensed clinical neuropsychologist.
The ability to comply with test directions, complete pre-operative task training, and provide informed consent.
Age 18-80 years.
Disqualifiers
None
Trial design
Treatments tested in this trial
- Deep Brain Stimulation
Treatment groups
120 Participants
are divided into 1 treatment groupSponsors and collaborators
Massachusetts Eye and Ear Infirmary
Lead sponsor
Massachusetts General Hospital
Collaborator
University of Utah
Collaborator
University of California, San Francisco
Collaborator
UMass Memorial Health
Collaborator
University of Iowa
Collaborator
Source ClinicalTrials.gov