Deep Sedation With Pre-emptive Endotracheal Intubation for Advanced Bronchoscopy Procedures

ConditionLung Diseases
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age19-90
SponsorPusan National University Yangsan Hospital

About this trial

Bronchoscopy is crucial for diagnosing and treating respiratory diseases and is recommended under sedation. Deep sedation improves patient comfort and procedural efficiency, especially in complex cases, by reducing movement and coughing. However, it carries risks of respiratory depression and airway obstruction, potentially requiring premature termination or urgent intubation. Determining the optimal timing for intubation can be challenging despite proper monitoring. To enhance safety, the investigator has performed bronchoscopy under deep sedation with preemptive intubation for years, sharing this experience with other hospitals. This study aims to evaluate its safety and feasibility through a multicenter prospective observational approach.

Eligibility criteria

Qualifiers

Patients requiring a bronchoscopy-assisted procedure for diagnostic or therapeutic purposes

Individuals who voluntarily consent to participate in the clinical study and sign a written informed consent form

Disqualifiers

Patients who have experienced acute myocardial infarction or acute stroke within the past six weeks

Patients with contraindications to bronchoscopy (e.g., severe respiratory or cardiovascular comorbidities)

Patients with a history of allergy to benzodiazepines, propofol, fentanyl, or flumazenil

Patients with genetic disorders such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption

Trial design

Treatments tested in this trial

  • Deep Sedation Under Proceduralist Direction with Pre-emptive Endotracheal Intubation

Treatment groups

203 Participants
are divided into 1 treatment group