About this trial
Bronchoscopy is crucial for diagnosing and treating respiratory diseases and is recommended under sedation. Deep sedation improves patient comfort and procedural efficiency, especially in complex cases, by reducing movement and coughing. However, it carries risks of respiratory depression and airway obstruction, potentially requiring premature termination or urgent intubation. Determining the optimal timing for intubation can be challenging despite proper monitoring. To enhance safety, the investigator has performed bronchoscopy under deep sedation with preemptive intubation for years, sharing this experience with other hospitals. This study aims to evaluate its safety and feasibility through a multicenter prospective observational approach.
Eligibility criteria
Qualifiers
Patients requiring a bronchoscopy-assisted procedure for diagnostic or therapeutic purposes
Individuals who voluntarily consent to participate in the clinical study and sign a written informed consent form
Disqualifiers
Patients who have experienced acute myocardial infarction or acute stroke within the past six weeks
Patients with contraindications to bronchoscopy (e.g., severe respiratory or cardiovascular comorbidities)
Patients with a history of allergy to benzodiazepines, propofol, fentanyl, or flumazenil
Patients with genetic disorders such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption
Trial design
Treatments tested in this trial
- Deep Sedation Under Proceduralist Direction with Pre-emptive Endotracheal Intubation