Deep TMS of Neural Circuits Associated With Stimulant Use Disorder
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age25-75
SponsorStanford University
About this trial
This study aims to evaluate the efficacy of deep transcranial magnetic stimulation (dTMS) as a treatment for Veterans with a methamphetamine use disorder (MUD).
Eligibility criteria
Qualifiers
Must be within the age range of 25-75.
Participants must meet Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) criteria for moderate to severe MUD (≥4 diagnostic symptoms).
Participants must be able to obtain a Motor Threshold (MT), which will be determined during the screening process.
Participants must have an adequately stable condition and environment to enable attendance at scheduled clinic visits.
Disqualifiers
Transcranial magnetic stimulation (TMS) and magnetic resonance imaging (MRI) contraindications: such as a cardiac pacemaker, cochlear implant, or an implanted device (deep brain stimulation, ferromagnetic metal in the head and body, claustrophobia, pregnant or breastfeeding or other ferromagnetic device/object in the head and body within 30 cm of the treatment coil.
General medical condition, disease, or neurological disorder that interferes with the assessments or participation.
Unable to safely withdraw, at least two weeks prior to treatment, from medications that increase seizure risk.
Current substance abuse as determined by positive toxicology screen
Trial design
Treatments tested in this trial
- Deep Transcranial Magnetic Stimulation (dTMS) H4 coil - Active
- Deep Transcranial Magnetic Stimulation (dTMS) H4 coil - Sham
Treatment groups
30 Participants
are divided into 2 treatment groupsSponsors and collaborators
Stanford University
Lead sponsor
VA Palo Alto Health Care System
Collaborator
Source ClinicalTrials.gov