Defining the Role of Palliative carE for Patients With Hematologic Malignancies Undergoing Adoptive CEllular Therapy

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMassachusetts General Hospital

About this trial

The goal of this study is to determine whether a palliative care intervention (PEACE) can improve the quality of life and experiences of participants with Lymphoma, Leukemia, or Multiple Myeloma receiving adoptive cellular therapy (ACT). After completion of an open pilot, participants will be randomly assigned into one of two study intervention groups.

The names of the study intervention groups involved in this study are:

* Palliative care (PEACE) plus usual oncology care * Usual care (standard oncology care)

Participation in this research study is expected to last for up to 2 years.

It is expected that about 90 people will take part in this research study.

Eligibility criteria

Qualifiers

Age 18 years or older.

Ability to complete surveys in English or with assistance of an interpreter.

Diagnosis of a hematologic malignancy.

Receiving autologous adoptive cellular therapy (ACT) at MGH with an FDA approved cellular therapy product.

Disqualifiers

Impaired cognition or uncontrolled mental illness that prohibits study compliance based on the oncology clinician assessment.

Already receiving palliative care (PC).

Trial design

Treatments tested in this trial

  • Palliative Care
  • Usual Care

Treatment groups

90 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Massachusetts General Hospital

Lead sponsor

Conquer Cancer Foundation

Collaborator