Defining TRPV4 Contribution of Schwann Cells to Oral Cancer Pain
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorNew York University
About this trial
This is a prospective study involving human participants. Pressure and stretch sensitivity measures between oral cancer patients and healthy subjects will be compared. Pain stimulation will be conducted on the site of the cancer in 40 oral cancer patients, and on the tongue in 40 healthy volunteers, using pressure and stretch sensitivity tests.
Eligibility criteria
Qualifiers
Provide signed and dated informed consent form
Willing to comply with all study procedures and be available for the duration of the study
Male or female, at least 18 years of age
In good general health as evidenced by medical history
Disqualifiers
Clinically and/or histologically proven oral pre-cancer, oral cancer
Pregnancy or lactation (Female subjects of child-bearing potential will have a rapid urine pregnancy test)
Anything that would place the individual at increased risk or preclude the individual's full compliance with or completion of the study.
History of prior surgical, chemotherapeutic, or radiation treatment for head and neck cancer
Trial design
Treatments tested in this trial
- Pressure and stretch sensitivity testing
Treatment groups
80 Participants
are divided into 2 treatment groupsSponsors and collaborators
New York University
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
Collaborator
Source ClinicalTrials.gov