Definitive Radiation Therapy for Inoperable Breast Cancer
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18+
SponsorAlexander Stessin
About this trial
The purpose of this study is to find out if adding radiation therapy to routine medications for breast cancer helps in reducing and preventing the cancer from getting worse. Patients with a locally advanced breast cancer who cannot, or do not want to, undergo surgery are eligible to participate. Participation in this study does not prevent you from undergoing surgery in the future.
Eligibility criteria
Qualifiers
Biopsy proven invasive carcinoma of the breast, either lobular, ductal and/or no special type
T1-T4, N0-2, M0-1 invasive breast carcinoma by radiological or clinical criteria
Cancer is deemed unresectable, or the patient is a poor surgical candidate as determined following evaluation by a surgeon, or patient declines surgery.
Life expectancy > 6 months
Disqualifiers
Concurrent systemic therapy (except for endocrine therapy, HER2-targeted therapy, or immunotherapy which are permitted)
Prior radiation to ipsilateral breast or regional nodes
Inability to receive study treatment planning and treatment secondary to body habitus
Trial design
Treatments tested in this trial
- Whole breast radiation with simultaneous integrated boost (WB-SIB) to primary breast tumor
- Whole breast radiation with simultaneous integrated boost (WB-SIB) to primary breast tumor and ipsilateral axillary lymph nodes
Treatment groups
30 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov