The purpose of this study is to compare two strategies for treating adults with suspected large vessel occlusion stroke within 7 hours of symptom onset. Researchers will evaluate whether direct transfer to the neurointerventional angiography suite improves recovery and reduces disability compared to the conventional approach of first being evaluated in the emergency department. The study will also assess safety and other health outcomes to guide care for stroke patients.
Age: ≥ 18 years of age.
Clinical Presentation: Present to a participating TSC with signs or symptoms suggestive of acute LVO stroke.
Stroke Severity: Baseline NIHSS of 10 or higher.
Time since LKW: Time from LKW to arrival at the TSC must be within 7 hours.
Time Restrictions: Presentation to a thrombectomy-capable center more than 7 hours from LSW.
Imaging Criteria for Interfacility Transfer Patients: At sites enrolling transfer patients, any patient arriving from an outside hospital with time from imaging study at the presenting hospital to arrival at the TSC not exceeding 90 minutes.
Hemorrhagic Stroke: Presence of intracranial hemorrhage on brain imaging in the conventional strategy as Heidelberg that renders thrombectomy contraindicated.
Santiago Ortega Gutierrez
Lead sponsor
University of Iowa
Sponsor institution
Patient-Centered Outcomes Research Institute
Collaborator