Denervation for Osteoarthritis in the PIP-joint Efficacy Study (DOPS)
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorKarolinska Institutet
About this trial
The goal of this clinical trial is to compare the effects of a surgical and a non-surgical treatment method in patients with osteoarthritis in the proximal interphalangeal (PIP) joint. The main questions it aims to answer are:
* Are the treatments effective? * Is the surgical treatment more effective than the non-surgical treatment? Participants will receive surgical treatment (PIP joint denervation) or non surgical treatment (patient education plus exercise).
Researchers will compare the non-surgical and surgical groups to see if pain, patient-reported function, quality of life, movement and grip strength differs between the groups.
Eligibility criteria
Qualifiers
Age ≥ 18 years.
Chronic symptomatic osteoarthritis in the PIP-joint.
Radiological signs of osteoarthritis on posteroanterior and lateral radiographs assessed by the Kellgren-Lawrence classification (grade II-IV) (Kellgren & Lawrence, 1957).
Clinical signs of PIP-joint arthritis.
Disqualifiers
Inflammatory arthritis.
Ongoing infection in the hand.
Inability to co-operate with the follow-up protocol.
Intra-articular glucocorticoid, PRP or Hyaluronic acid injections in the affected joint less than 3 months prior to enrollment.
Trial design
Treatments tested in this trial
- PIP joint denervation
- Patient education plus exercise
Treatment groups
90 Participants
are divided into 2 treatment groupsSponsors and collaborators
Karolinska Institutet
Lead sponsor
Stockholm South General Hospital
Collaborator
Source ClinicalTrials.gov