Depression and Driving

ConditionsDepressionDrive
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age65+
SponsorWashington University School of Medicine

About this trial

This project will assess how depression, preclinical AD, and antidepressants affect driving behavior in cognitively normal older adults (65 years).

Eligibility criteria

Qualifiers

Drive on average at least once per week

Has a valid driver's license

Willing to complete blood draw

Willing to complete either lumbar puncture or PET imaging

Disqualifiers

Not willing to complete blood draw and/or one other biomarker

Less than 65 years of age

Does not drive a vehicle/ is no longer actively driving

Trial design

Treatments tested in this trial

  • F 18 AV-1451 (Flortaucipir)
  • [11C]-Pittsburgh Compound B ([11C]PiB)

Treatment groups

150 Participants
are divided into 2 treatment groups