Depth of Sedation and Its Impact on Cerebrovascular Reactivity in Acute Respiratory Distress Syndrome: a Pilot Analysis

ConditionARDS, Human
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Manitoba

About this trial

Investigation of the feasibility of monitoring processed transcutaneous electroencephalography (EEG), a method of interpreting brain activity, and near-infrared spectroscopy (NIRS), a method of determining levels of tissue oxygenation (StO2) in the brain, for patients with acute respiratory distress syndrome (ARDS) in the ICU.

Eligibility criteria

Qualifiers

Adult patient admitted to the ICU

ARDS confirmed according to the Berlin Definition

Invasive mechanical ventilation

Deep sedation and/or neuromuscular blockade required for ARDS treatment at the discretion of the treating medical team

Disqualifiers

More than 24 hours elapsed since ICU admission

Death is deemed imminent and inevitable during the next 24 hours

Known allergy to a textile component of the device

Consent declined from patient or authorized third party

Trial design

Treatments tested in this trial

  • Masimo O3 NIRS cerebral oximetry and SedLine processed EEG

Treatment groups

40 Participants
are divided into 1 treatment group

Sponsors and collaborators