Describing the Effect of Familiar Song on Arousal and Awareness for Children With Disorders of Consciousness (DoC)

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age1-18
SponsorMurdoch Childrens Research Institute

About this trial

The goal of this clinical trial is to compare the effect of live music therapy and recorded music on recovery of consciousness in children aged 1 to 18 years who have a disorder of consciousness (DoC) after a severe brain injury. Researchers also want to learn how children respond during music and noise, whether early responses to music are linked to recovery at 6 months, and how parents experience music therapy during their child's hospital stay at The Royal Children's Hospital (RCH) in Melbourne.

Participants will:

* Take part in a 10-day study period while in hospital. On 8 of the 10 days, they will receive either live or recorded familiar music in random order. Their level of consciousness will be measured before and after each session using a simple behavioural checklist. On the other 2 days, they will take part in video-recorded sessions to compare behavioural responses during live music, recorded music, and white noise. Videos will help capture small changes in movement, eye gaze, or facial expression. * Have their level of consciousness checked again at 6 months after injury to see if early responses relate to later recovery.

Parents and caregivers will be invited to take part in an interview about their experiences and observations of music therapy with their child.

This study will help researchers understand whether live music therapy provides benefits beyond recorded music and will guide how music therapy is best used to support children and families during recovery from severe brain injury.

Eligibility criteria

Qualifiers

Glasgow Coma Scale (GCS) 3-8 at admission to RCH

Mass pathology evident on neuroimaging

Expert opinion of treating consultant

Rancho Los Amigos Scale I, II, III or IV

Disqualifiers

ABI not compatible with life/child expected to die

ABI resulting from suspected non-accidental causes, including assault/abuse

Diagnosed premorbid or acquired severe hearing loss

Inability or unwillingness of legally acceptable representative to give written informed consent

Trial design

Treatments tested in this trial

  • Live Music Therapy
  • Recorded Music

Treatment groups

10 Participants
are divided into 2 treatment groups