About this trial
The goal of this one-arm clinical trial is to determine whether participants with mild cognitive impairment (MCI) can successfully navigate a virtual reality (VR) maze. The VR maze is designed as a training tool aimed at improving participants' spatial navigation abilities.
Main Aims:
1. To determine whether at least 70% of older adults enrolled in the study can complete twenty-four 50-minute training sessions over a 4-month period. 2. To assess whether combining virtual reality with EEG recordings can be used to measure brain activation and changes in brain activation associated with spatial navigation learning.
Participants will:
1. Walk in an open, unobstructed space while wearing VR goggles. 2. Explore up to fifty different virtual mazes in sequence and attempt to find their way through each one.
Eligibility criteria
Qualifiers
Age 65 and older with amnestic mild cognitive impairment (aMCI);
Can speak English;
Agrees to MoBI recording;
Normal or corrected-to-normal vision/audition;
Disqualifiers
Dementia (Memory Impairment/AD8 screen);
Medical conditions that affect participation such as vertigo and neck pain;
Hospitalization in the past six months or plans for surgery affecting participation in the next four months;
Mobility limitations solely due to musculoskeletal limitation or pain;
Trial design
Treatments tested in this trial
- Spatial Navigation training
Treatment groups
Sponsors and collaborators
Albert Einstein College of Medicine
Lead sponsor
National Institute on Aging (NIA)
Collaborator