Detecting Fatigue From Voice in Generalised Myasthenia Gravis
ConditionMyasthenia Gravis Generalised
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorThymia Limited
About this trial
The goal of this observational study is to learn if computer analysis of voice recordings can detect a type of exhaustion called "central fatigue" in adults with generalised myasthenia gravis.
The main questions it aims to answer are:
1. Can advanced voice analysis accurately tell when participants are experiencing deep exhaustion based on how they speak? 2. How easy and acceptable is voice-based fatigue monitoring for people with myasthenia gravis?
Participants will:
1. Record themselves reading short passages and answering questions out loud twice daily (morning and evening), twice a week, for 4 weeks. 2. Answer brief questionnaires about their energy levels, mood, and myasthenia gravis symptoms during each session. 3. Use their own devices (computer, tablet, or smartphone) to complete all study activities online from home.
Eligibility criteria
Qualifiers
Adults ≥18 years old
Self-reported generalised Myasthenia Gravis diagnosis confirmed by healthcare provider for ≥6 months
Disease stability for ≥6 months (no hospitalisations, medication changes, or significant symptom worsening)
English as first language
Disqualifiers
Pure ocular Myasthenia Gravis
Diagnosed mild cognitive impairment or dyslexia
Speech or hearing impairments affecting voice recording
Unable to provide credible diagnostic information (healthcare provider diagnosis, antibody test results, current medications)
Trial design
Treatments tested in this trial
- Not listed
Trial groups
No trial groups listed
Locations
Sponsors and collaborators
Thymia Limited
Lead sponsor
UCB Pharma
Collaborator
Source ClinicalTrials.gov