About this trial
An inflammatory component associated with AMD has been highlighted by genetic associations of predisposition to AMD, as well as by the recently demonstrated link between AMD and periodontitis.
Some patients followed at the Fondation Adolphe de Rothschild Hospital for wet AMD seemed to show an improvement of neovascular activity (less need for intravitreal injections of anti-VEGF) after treatment of their sinusitis.
The investigators would therefore like to assess the link between AMD and sinusitis, an infection close to the site of AMD.
Eligibility criteria
Qualifiers
Age ≥ 18 years
Patient followed and treated for at least 2 years for bilateral neovascular form of age-related macular degeneration (AMD)
At least one eye treated with ≥ 6 intravitreal injections during the year preceding preinclusion
Express consent to participate in the study
Disqualifiers
Persons referred to in articles L1121-5 to L1121-8 of the CSP (corresponding to all protected persons: pregnant women, parturients, nursing mothers, persons deprived of liberty by judicial or administrative decision, minors, and persons under legal protection: guardianship or curatorship).
Severe myopia (> 6 diopters)
Patient already being treated for acute or chronic sinusitis
History of central serous chorioretinopathy or diffuse retinal epitheliopathy
Trial design
Treatments tested in this trial
- sinusitis screening consultation