dEtection of rheumAtoid aRthritis - Interstitial Lung dIseasE by Thoracic ultRasound
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital, Tours
About this trial
Rheumatoid arthritis is an autoimmune disease that can affect various organs, including the lungs, and lead to rheumatoid arthritis-interstitial lung disease (RA-ILD).
RA-ILD is responsible for increased mortality in rheumatoid arthristis (RA) patients.
The prevalence of RA-ILD varies according to the screening tool used.
The current gold standard is chest CT, but this is an expensive, time-consuming and irradiating examination, and recommendations on when and how often it should be performed are not clearly established.
Lung ultrasound (LUS) is an emerging tool for the detection of lung parenchymal damage, particularly in systemic scleroderma and idiopathic pulmonary fibrosis (IPF).
LUS is a non-irradiating, non-expensive examination that can be performed rapidly.
The aim of our study is to evaluate LUS as a screening tool for RA-ILD, in patients with risk factors for developing RA-ILD.
Eligibility criteria
Qualifiers
Adult patient (age > 18 years) followed at CHU of Tours
Diagnosis of rheumatoid arthritis validated according to ACR 2010 criteria, EULAR classification, regardless of time since diagnosis
Patient who has had or will have a thoracic CT scan and PFT performed as part of routine care in the 6 months preceding or following inclusion
Male sex or
Disqualifiers
Diagnosis of congenital lung disease
Diagnosis of another autoimmune pathology associated with RA (overlap syndrome) linked to the development of ILD (interstitial lung disease) (systemic sclerosis, myositis, dermatomyositis, mixed connectivitis, systemic lupus erythematosus or other ANCA vasculitis, with the exception of secondary Gougerot-Sjögren's syndromes).
Current or operated lung cancer
Thoracic irradiation
Trial design
Treatments tested in this trial
- Lung ultrasound (LUS)
Treatment groups
No treatment groups listed
Sponsors and collaborators
Source ClinicalTrials.gov