Detection of Small Fiber Neuropathy Using Skin Properties

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorBrigham and Women's Hospital

About this trial

Small fiber neuropathy affects millions of peoples worldwide. The neuropathy is causing disabling burning pain and dysautonomia such as dizziness with standing, brain fog, fatigue, constipation, too much or too little sweating. The detection of nerve damage is complicated and not widely available; it requires either skin biopsy or specialized equipment and training. This project utilizes the mathematical processing of skin pictures for the purpose to extract the statistical features related to loss of small fibers. This approach can improve the availability of diagnosis of small fiber neuropathy.

Eligibility criteria

Qualifiers

Patients with age 18 year or older

Patients that sign the informed consent form to participate in this study

Patients completed the autonomic testing with skin biopsies

Disqualifiers

Patients with significant hairs at the legs that will cover the skin

Any dermatological disorder that can affect the skin composition

The use of skin lotion

Trial design

Treatments tested in this trial

  • Image processing of skin

Treatment groups

No treatment groups listed

Sponsors and collaborators