About this trial
Small fiber neuropathy affects millions of peoples worldwide. The neuropathy is causing disabling burning pain and dysautonomia such as dizziness with standing, brain fog, fatigue, constipation, too much or too little sweating. The detection of nerve damage is complicated and not widely available; it requires either skin biopsy or specialized equipment and training. This project utilizes the mathematical processing of skin pictures for the purpose to extract the statistical features related to loss of small fibers. This approach can improve the availability of diagnosis of small fiber neuropathy.
Eligibility criteria
Qualifiers
Patients with age 18 year or older
Patients that sign the informed consent form to participate in this study
Patients completed the autonomic testing with skin biopsies
Disqualifiers
Patients with significant hairs at the legs that will cover the skin
Any dermatological disorder that can affect the skin composition
The use of skin lotion
Trial design
Treatments tested in this trial
- Image processing of skin