About this trial
The main objective of this study is to identify epigenetic markers specific to abnormal myeloid cells in patients with acute myeloid leukemia (AML) by analyzing the methylation of circulating cell-free DNA in plasma.
Eligibility criteria
Qualifiers
/ Control Group
Age ≥ 60 years;
Scheduled for cardiac surgery involving sternotomy;
Normal blood count within the two months preceding sampling;
Disqualifiers
Patients deemed unsuitable for sampling by the surgeon performing the procedure;
Patients under legal protection measures;
Patients under judicial supervision or deprived of liberty by judicial or administrative decision;
Presence of positive virological markers indicating active infection (hepatitis B, hepatitis C, or HIV).
Trial design
Treatments tested in this trial
- Epigenetic markers
Treatment groups
Sponsors and collaborators
Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
Lead sponsor
Institut de Recherche en Hématologie et Transplantation (IRHT)
Collaborator