About this trial
The purpose of this study is to collect information about opioid craving so that the investigators can develop an opioid craving assessment to improve treatments for individuals with opioid use disorder. To collect this information, the investigators are recruiting individuals in treatment for opioid use disorder who will complete cue-induced opioid craving tasks where these individuals will: (1) look at pictures of neutral objects and touch neutral objects (e.g., water bottles or flashlights), (2) look at opioid-related images, and (3) look and touch opioid-related objects. Participants will then complete a one-on-one interview about the thoughts, feelings and physical sensations the participants experienced during the cue-induced craving session. Participants will also complete questionnaires and existing opioid craving assessments. Finally, participants will provide formal feedback about existing opioid craving assessments with cognitive interviews.
Eligibility criteria
Qualifiers
18 years of age and older
Opioid-positive urine sample at admission visit (excluding individuals receiving Naltrexone).
Current opioid use disorder per Diagnostic Statistical Manual (DSM)-5
Currently in treatment for opioid use disorder
Disqualifiers
Being pregnant or breastfeeding, or may become pregnant during the trial
History of psychosis or mania or other serious psychiatric disorders assessed by the Mini International Neuropsychiatric Interview
Past 30-day suicidal behavior assessed by the Columbia Suicide Severity Rating Scale
Have circumstances that would interfere with study participation (e.g., impending jail).
Trial design
Treatments tested in this trial
- Neutral Cue-induced Craving
- Visual Opioid Cue-induced Craving
- Visual and Tactile Opioid Cue-induced Craving
Treatment groups
Sponsors and collaborators
Johns Hopkins University
Lead sponsor
National Institute on Drug Abuse (NIDA)
Collaborator