This study aims to develop and validate a culturally appropriate, reliable, and clinically applicable patient-reported outcome (PRO) instrument to assess quality of life in patients with pulmonary arterial hypertension (PAH) in China.
The study includes two phases: (1) scale development using literature review, Delphi expert consultation, and patient interviews; and (2) multicenter prospective observational validation to evaluate reliability, validity, and responsiveness.
The final scale is expected to support clinical assessment, treatment monitoring, and health policy decision-making.
Age ≥18 years
Diagnosed with pulmonary arterial hypertension
Able to read and complete questionnaires
Provided informed consent
Severe physical condition preventing participation
History of psychiatric disorders or current use of psychiatric medication
Pregnancy or lactation
Any condition preventing completion of questionnaires