Early prediction of acute kidney injury (AKI) may provide a crucial opportunity for AKI prevention. To date, no prediction model targeting AKI among general hospitalized patients in developing countries has been published. We developed a simple, real-time, interpretable AKI prediction model for general hospitalized patients from a large tertiary hospital in China, and validated it across five independent, geographically distinct, different tiered hospitals.
Adult patients (18 years and older) admitted to five hospitals during the study period
Have less than 2 documented serum creatinine (Scr) measurements during hospitalization
Being diagnosed with end-stage renal disease (ESRD)
Maintained on dialysis or had an initial Scr greater than or equal to 4.0 mg/dL at admission
Developed AKI prior to admission or within 24 hours after admission