Development of a Biomarker Panel for the Earlier Prediction of Acute Kidney Injury in Patients With Diabetes

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorBarts & The London NHS Trust

About this trial

Patients living with diabetes mellitus have double the risk of kidney failure compared to patients without diabetes following use of dye in many x-rays and procedures to diagnose and treat narrowing of the arteries (blood vessels) in the heart that can lead to angina or a heart attack. Heart disease is the commonest cause of death in patients with diabetes. People with diabetes are more likely to need these tests/treatments. By identifying those at greater risk of kidney complications we may be able to make these tests/treatments safer and offer them to more patients with diabetes.

Eligibility criteria

Qualifiers

Age > 18 years, known diabetes mellitus or BM on arrival consistent with probable diagnosis of diabetes, eGFR <60 ml/min

Undergoing a PCI procedure

Agrees to the additional collection of blood and urine samples as outlined above

Agrees to access of their clinical records for the collection of relevant medical data

Disqualifiers

Cardiogenic shock

Pregnancy

Patient on renal replacement therapy (haemodialysis/CAPD/renal transplant)

Known clinically significant infection such as HIV, Hepatitis or TB

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

250 Participants
are grouped into 1 trial group

Sponsors and collaborators