About this trial
In this project, ocular motor, pupil and gait data in people with Parkinson's disease (PD) will be collected in order to develop machine learning models for the diagnosis and monitoring of PD. With this, the investigators aim to advance the state of the art in PD diagnosis and monitoring. By integrating the principles of machine learning with high-quality sensor data, more accurate and earlier diagnosis could potentially be achieved. Ocular motor and pupil data will be collected with the standard clinical examination and with neos, a medical device approved for objective ocular motor and pupil measurement. Gait will be collected using an IMU sensor and GaitQ senti, a consumer device that allows for an objective and continuous remote gait monitoring.
Eligibility criteria
Qualifiers
Diagnosis of idiopathic Parkinson's disease (UK Brain Bank Criteria) or other appropriate condition specific scale [stroke, multiple sclerosis, arthritis or osteoporosis]
Able to self-report history of daily gait freezing and/or festination for people with PD or gait and/or transfers affected by condition
Able to walk unsupported or using an aid for at least 5 minutes and satisfactory completion of the Canadian PARQ and if over 69 used to carrying out this level of exercise
Adult (+18 years old)
Disqualifiers
Any physical or mental condition affecting ability to safely participate in this level of activity and capacity to understand testing as demonstrated by ability to safely follow commands and pass the PARQ by the research team.
Cognitive impairment affecting ability to safely participate and follow instructions
Any injury or disorder that may affect balance (other than Parkinson's or referring primary condition)
Any skin conditions or broken skin in the calf and behind knee area
Trial design
Treatments tested in this trial
- gait with cueing wearable device and neuro-ocular performance
Treatment groups
Sponsors and collaborators
University of Exeter
Lead sponsor
University of Zurich
Collaborator
University Hospital, Zürich
Collaborator
machineMD AG
Collaborator
GaitQ company
Collaborator