Development of Digital Services for Parkinson's Disease

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Exeter

About this trial

In this project, ocular motor, pupil and gait data in people with Parkinson's disease (PD) will be collected in order to develop machine learning models for the diagnosis and monitoring of PD. With this, the investigators aim to advance the state of the art in PD diagnosis and monitoring. By integrating the principles of machine learning with high-quality sensor data, more accurate and earlier diagnosis could potentially be achieved. Ocular motor and pupil data will be collected with the standard clinical examination and with neos, a medical device approved for objective ocular motor and pupil measurement. Gait will be collected using an IMU sensor and GaitQ senti, a consumer device that allows for an objective and continuous remote gait monitoring.

Eligibility criteria

Qualifiers

Diagnosis of idiopathic Parkinson's disease (UK Brain Bank Criteria) or other appropriate condition specific scale [stroke, multiple sclerosis, arthritis or osteoporosis]

Able to self-report history of daily gait freezing and/or festination for people with PD or gait and/or transfers affected by condition

Able to walk unsupported or using an aid for at least 5 minutes and satisfactory completion of the Canadian PARQ and if over 69 used to carrying out this level of exercise

Adult (+18 years old)

Disqualifiers

Any physical or mental condition affecting ability to safely participate in this level of activity and capacity to understand testing as demonstrated by ability to safely follow commands and pass the PARQ by the research team.

Cognitive impairment affecting ability to safely participate and follow instructions

Any injury or disorder that may affect balance (other than Parkinson's or referring primary condition)

Any skin conditions or broken skin in the calf and behind knee area

Trial design

Treatments tested in this trial

  • gait with cueing wearable device and neuro-ocular performance

Treatment groups

80 Participants
are divided into 1 treatment group

Sponsors and collaborators

University of Exeter

Lead sponsor

University of Zurich

Collaborator

University Hospital, Zürich

Collaborator

machineMD AG

Collaborator

GaitQ company

Collaborator