DEXDES Trial: Dexmedetomidine-Desflurane Combination in Laparoscopic Colectomy
ConditionColorectal Neoplasms
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorTam Anh Research Institute
About this trial
This randomized double-blind controlled clinical trial aims to evaluate the efficacy and safety of combining Dexmedetomidine with Desflurane in patients undergoing elective laparoscopic colectomy. The study will assess whether the combination can reduce Desflurane consumption, improve intraoperative hemodynamic stability, and enhance postoperative recovery compared to Desflurane alone.
Eligibility criteria
Qualifiers
Age 18-65 years
ASA Physical Status I-II
Elective laparoscopic colectomy
Written informed consent provided
Disqualifiers
Severe cardiac, hepatic, or renal disease
COPD or bronchial asthma
Chronic opioid or psychotropic medication use
Atrioventricular block (grade II-III), sick sinus syndrome
Trial design
Treatments tested in this trial
- Dexmedetomidine + Desflurane
- Desflurane + Normal Saline
Treatment groups
40 Participants
are divided into 2 treatment groupsSponsors and collaborators
Tam Anh Research Institute
Lead sponsor
Tam Anh TP. Ho Chi Minh General Hospital
Collaborator
Source ClinicalTrials.gov