Dexmedetomidine and Dexamethasone Added as Adjuvant Infraclavicular Brachial Plexus Block in Upper Limb Surgery

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-70
SponsorUmraniye Education and Research Hospital

About this trial

The aim of this study was to investigate the effect of dexmedetomidine and dexamethasone added during USG-guided infraclavicular block on block onset time, total block time and time to first analgesic need in patients undergoing upper extremity surgery.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

18-70 years

ASA I-II

Disqualifiers

Under 18 years of age and older than 70 years of age,

presence of brachial plexus injury,

patients with bleeding diathesis,

presence of allergy, -contralateral diaphragmatic paralysis, -

Trial population

A total of 44 adult patients 18 to 70 years, American Society of Anesthesiologists (ASA) I-II who underwent upper extremity surgery were included in Orthopedics and Traumatology Clinic.

Trial design

Design model

Case-control

Time perspective

Prospective

Treatments tested in this trial

  • Infraclavicular Block with Dexmedetomidine and Dexamethasone

    Procedure/Surgery

    Infraclavicular block with Dexmedetomidine and Dexamethasone was performed at least 30 min before the start of the operation. The patient was positioned in a supine position arms at the sides or in 90 degree abduction, head turned to the other side. Infraclavicular block was performed with the lateral sagittal technique, while the USG probe was placed under the clavicle and medial to the coracoid process, providing a brachial plexus image in the form of a hyperechoic outer ring and hypoechoic circles, like a classic honeycomb image. A local anesthetic mixture was injected with a 100 mm block needle with negative aspiration and its spread in tissue planes was observed. If the VAS score was 3 or above, tramadol 1 mg kg-1 was administered as an analgesic drug.

Treatment groups

44 Participants
are divided into 2 treatment groups
Group A: Group Dexmedetomidine: (n:22)1 intervention
Group B: GroupDexamethasone: (n:22)1 intervention

Trial outcomes

Primary outcomes

1

infraclavicular block onset time

Sensory block / motor block onset time

Time frame
24 -48 hours
2

postoperative analgesic drug requirement

opioid total amount micrograms

Time frame
24 -48 hours
3

infraclavicular total block time

block time hours

Time frame
24 -48 hours

Secondary outcomes

1

investigate the effects on VAS score and sedation level in the first 24 hours postoperatively

VAS score

Time frame
24 -48 hours
2

advers event Perioperative and postoperative period

Nausea,Vomiting,Hypotension,Bradycardia, Nerve damage

Time frame
24 -48 hours

Other outcomes

Sponsors and contacts

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