Dexmedetomidine as Adjuvant for Suprazygomatic Maxillary Nerve Block in Children's Adenotonsillectomy

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age2-7
SponsorMcGill University Health Centre/Research Institute of the McGill University Health Centre

About this trial

The goal of this clinic trial is to evaluate the impact of dexmedetomidine as an adjunct pain pain medication on opioid-free recovery in children undergoing adenotonsillectomy with Suprazygomatic maxillary nerve block (SZMB). The main questions it aims to answer are:

* Does SZMB with the local anesthetic ropivacaine and the adjuvant dexmedetomidine result in less pain * Is dexmedetomidine associated with an improved quality of recovery at home Researchers will compare pain in participants given an SZMB with ropivacaine and an adjuvant dexmedetomidine, participants given SZMB with ropivacaine only, and a SZMB with ropivacaine and dexmedetomidine given intravenously.

Participants will:

* Be given the SZMB during the surgery. * Be evaluated after surgery to measure their opioid consumption, pain severity, level of agitation, and level of delirium * Complete a daily questionnaire for 7 days after surgery on the patients pain and recovery

Eligibility criteria

Qualifiers

Scheduled for elective partial adenotonsillectomy,

STUBR score ≥ 3, indicating significant sleep-disordered breathing

Patients whose parents are fluent in French of English will be enrolled

Disqualifiers

Scheduled to undergo total extracapsular adenotonsillectomy or adenoidectomy-only procedures

Patient requires prolonged intubation postoperatively

the anesthesiologist does not adhere to the standardized anesthesia protocol

Patients with neurological or cardiac congenital deficits, with cardiac arrhythmias (non-sinus rhythm), implanted pacemakers, on chronic therapy with drugs that have known effects on sympathetic and parasympathetic activity (antimuscarinics, beta-2 adrenergic agonists, alpha-1 adrenergic antagonists or antiarrhythmic agents, tricyclic antidepressants)

Trial design

Treatments tested in this trial

  • Ropivacaine

Treatment groups

150 Participants
are divided into 3 treatment groups