Dexmedetomidine Versus Ketamine as Adjuvants in Bariatric Surgery

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorTanta University

About this trial

This randomized controlled trial aims to compare the analgesic efficacy of dexmedetomidine infusion versus low-dose ketamine infusion as adjuvants in bariatric surgery. The study includes 90 patients undergoing bariatric surgery at Menoufia University Hospital, randomized into three groups: dexmedetomidine, ketamine, and control (placebo). Primary outcomes include total morphine consumption intra- and post-operatively. Secondary outcomes include postoperative pain scores, total analgesic consumption, time to first analgesic request, hemodynamic parameters, and patient satisfaction. This study seeks to explore safer, more effective pain management strategies to minimize opioid use in bariatric surgery patients.

Eligibility criteria

Qualifiers

Patients aged 18-60 years.

Both sexes.

Body mass index (BMI) > 35 kg/m², scheduled for bariatric surgery.

American Society of Anesthesiologists (ASA) physical status I-II.

Disqualifiers

History of hypersensitivity to dexmedetomidine or ketamine.

History of substance abuse or chronic opioid use.

American Society of Anesthesiologists (ASA) physical status III or IV.

Severe hepatic or renal impairment.

Trial design

Treatments tested in this trial

  • Dexmedetomidine infusion
  • Ketamine infusion
  • Normal Saline Infusion (Placebo)

Treatment groups

90 Participants
are divided into 3 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

Tanta University

Lead sponsor

Menoufia University

Sponsor institution