Dexmedetomidine Versus Magnesium Sulfate Infusion in Craniotomy
ConditionCraniotomy Surgery
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorAssiut University
To compare the intraoperative effects of Dexmedetomidine and Magnesium Sulfate infusion on intracranial pressure and cerebral perfusion pressure in adult patients undergoing craniotomy
Age 18-65 years
Elective craniotomy for supratentorial pathology
No contraindication to lumbar drain insertion
Baseline mental status is stable, allowing for a reliable postoperative neurological evaluation can be done
Coagulopathy or current anticoagulation
Severe renal or hepatic dysfunction
Known allergy to study medications
traumatic brain injury