Dexmedetomidine Versus Magnesium Sulfate Infusion in Craniotomy

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorAssiut University

About this trial

To compare the intraoperative effects of Dexmedetomidine and Magnesium Sulfate infusion on intracranial pressure and cerebral perfusion pressure in adult patients undergoing craniotomy

Eligibility criteria

Qualifiers

Age 18-65 years

Elective craniotomy for supratentorial pathology

No contraindication to lumbar drain insertion

Baseline mental status is stable, allowing for a reliable postoperative neurological evaluation can be done

Disqualifiers

Coagulopathy or current anticoagulation

Severe renal or hepatic dysfunction

Known allergy to study medications

traumatic brain injury

Trial design

Treatments tested in this trial

  • Dexamedomedine
  • MgSO4

Treatment groups

60 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators