Diagnosis of Myocardial Ischemia With MCG Using SPECT as a Reference Standard
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorQilu Hospital of Shandong University
About this trial
This is a prospective clinical study aiming to investigate the efficacy of Magnetocardiography (MCG) in detecting myocardial ischemia in patients of a suspected non-ST-elevation-acute coronary syndrome (NSTE-ACS) by using Single photon emission computed tomography (SPECT) as the gold standard for determining the presence and severity of myocardial ischemia.
Eligibility criteria
Qualifiers
Age 18 years or older;
Patients with symptoms of myocardial ischemia such as angina pectoris, who have CAG showing <70% stenosis at the most severe site or CTA showing non-severe stenosis
Signed informed consent.
Disqualifiers
Patients with absolute or relative contraindications to SPECT-loaded myocardial perfusion, including acute myocardial infarction within 48 hours, significant left main coronary artery stenosis, bronchial asthma, and adenosine injection allergy;
Patients with Non-ischemic dilated cardiomyopathy, or hypertrophic cardiomyopathy, or moderate or severe valvular disease;
Patients with Hemodynamic instability (systolic blood pressure<90 mmHg, or who requires vasoactive drugs), or patients with tachyarrhythmia, Ⅱdegree atrioventricular block and above that have not returned to normal;
Patients who have severe renal abnormality with eGFR <30 ml/min, or patients who are on dialysis;
Trial design
Treatments tested in this trial
- Magnetocardiography
- Single photon emission computed tomography (SPECT)
Treatment groups
No treatment groups listed
Sponsors and collaborators
Qilu Hospital of Shandong University
Lead sponsor
Chongqing Emergency Medical Center
Collaborator
Source ClinicalTrials.gov