Diagnosis of Renal Osteodystrophy in Patients With Reduced Renal Function

ConditionRenal Osteodystrophy

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18+

SponsorDitte Hansen

About this trial

The aim of the study is to

1. To describe the bone morphology in patients with reduced renal function and high or low parathyroid hormone (PTH) respectively. 2. To investigate if the non-invasive method 18-Fluoride Positron Emission Tomography (18F-PET) can describe the bone turnover and reflect the bone histomorphologic changes 3. To investigate if non-oxidized PTH reflects bone turnover

Eligibility criteria

Qualifiers

estimated Glomerular Filtration Rate (eGFR) ≤ 20 ml/min/1,73m2

PTH < 150 pg/ml or PTH > 300 pg/ml

Disqualifiers

ongoing malignancy

Allergy towards tetracyclin

Pregnancy

eGFR >= 60 ml/min

Trial design

Treatments tested in this trial

18F-PET

Treatment groups

40 Participants

are divided into 3 treatment groups

Sponsors and collaborators

Ditte Hansen

Lead sponsor

Herlev Hospital

Sponsor institution

University of Copenhagen

Collaborator

Universiteit Antwerpen

Collaborator

Source ClinicalTrials.gov