Diagnosis of Tuberculosis in Swiss Children
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeUp to 17
SponsorUniversity Children's Hospital Basel
About this trial
1. The primary objective is to improve the sensitivity of novel immunodiagnostic tests for detection of TB disease in children. 2. The secondary objective is to determine biomarkers that discriminate children with TB infection and disease.
Eligibility criteria
Qualifiers
all children / adolescents < 18 years of age undergoing evaluation for TB exposure, infection or disease.
Disqualifiers
children / adolescents with TB infection or disease who have already been started on anti-mycobacterial treatment, children who have been treated for TB previously.
Trial design
Treatments tested in this trial
- Secreted cytokine assay
- Intracellular cytokine assay
Treatment groups
190 Participants
are divided into 3 treatment groupsSponsors and collaborators
University Children's Hospital Basel
Lead sponsor
Ospedale Regionale Bellinzona e Valli
Collaborator
Insel Gruppe AG, University Hospital Bern
Collaborator
University of Lausanne Hospitals
Collaborator
University Hospital, Geneva
Collaborator
Luzerner Kantonsspital
Collaborator
Cantonal Hospital of St. Gallen
Collaborator
University Children's Hospital, Zurich
Collaborator
Kantonsspital Aarau
Collaborator
Source ClinicalTrials.gov