Diagnostic Cervical Conization for Persistent Infection or Integration of HPV

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age25-70
SponsorTongji Hospital

About this trial

For the patients with cervical persistent infection or integration of HPV, we has designed a program to perform cervical conization for certain patients to earlier and better diagnose and cure the diseases of HPV infection and related cervical intraepithelial neoplasia/cancer.

Eligibility criteria

Qualifiers

The patients are referred to colposcopy and biopsy examinations due to abnormal cervical screening results with no precancerous lesions discovered by pathology.

The course of HPV type 16/18 persistent infection is more than two years.

The integration reads of HPV is more than 15.

The impression of colposcopy indicates precancerous lesions.

Disqualifiers

Pregnant women.

Vaginal intraepithelial neoplasia is highly suspected by colposcopy and pathological examinations.

The patients are suffering malignant tumors of other system and have not been cured.

There is acute inflammation of the lower genital or anal tract.

Trial design

Treatments tested in this trial

  • diagnostic cervical conization

Treatment groups

250 Participants
are divided into 1 treatment group

Sponsors and collaborators

Tongji Hospital

Lead sponsor

National Natural Science Foundation of China

Collaborator