About this trial
For the patients with cervical persistent infection or integration of HPV, we has designed a program to perform cervical conization for certain patients to earlier and better diagnose and cure the diseases of HPV infection and related cervical intraepithelial neoplasia/cancer.
Eligibility criteria
Qualifiers
The patients are referred to colposcopy and biopsy examinations due to abnormal cervical screening results with no precancerous lesions discovered by pathology.
The course of HPV type 16/18 persistent infection is more than two years.
The integration reads of HPV is more than 15.
The impression of colposcopy indicates precancerous lesions.
Disqualifiers
Pregnant women.
Vaginal intraepithelial neoplasia is highly suspected by colposcopy and pathological examinations.
The patients are suffering malignant tumors of other system and have not been cured.
There is acute inflammation of the lower genital or anal tract.
Trial design
Treatments tested in this trial
- diagnostic cervical conization
Treatment groups
Sponsors and collaborators
Tongji Hospital
Lead sponsor
National Natural Science Foundation of China
Collaborator